Neoral induction in pediatric renal transplantation

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Comparison of polyclonal induction agents in pediatric renal transplantation.

Collective pediatric data suggest that anti-T-cell induction therapy with polyclonal antibodies improves the outcome of both short- and long-term renal allograft survival. Polyclonal agents, including thymoglobulin (Thy), a rabbit anti-thymocyte globulin; Minnesota (horse) anti-lymphoblast globulin (ALG); and ATGAM, a horse anti-thymocyte globulin (ATG), all suppress B and T cells. While no spe...

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Advances in Pediatric Renal Transplantation

The science of kidney transplantation in children has advanced remarkably in the last 40 years [1, 2]. As kidney transplants in adult recipients were becoming more common with improving shortand long-term outcomes, results in children were lagging behind. This lag was attributed to multiple factors: greater surgical and technical problems in small children, different metabolism for needed drugs...

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Alemtuzumab induction in renal transplantation.

BACKGROUND There are few comparisons of antibody induction therapy allowing early glucocorticoid withdrawal in renal-transplant recipients. The purpose of the present study was to compare induction therapy involving alemtuzumab with the most commonly used induction regimens in patient populations at either high immunologic risk or low immunologic risk. METHODS In this prospective study, we ra...

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Induction treatment in renal transplantation.

DOI: 10.5935/0101-2800.20150025 Induction immunosuppression in renal transplant means the administration of large doses of immunosuppressive agents immediately before and/or after transplantation. Although conceptually total body irradiation, high doses of corticosteroids and even plasmapheresis carried out at the time of transplantation characterize induction treatments in renal transplantatio...

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Pediatric renal transplantation--Indian experience.

OBJECTIVE To analyze our experience with renal transplantation in children with end-stage renal disease (ESRD) in India. DESIGN Retrospective study. METHODS Over the last 7.5 years, 27 renal transplants were performed on children below 12 years of age, 8 children were less than 6 years old, 19 were between 6 and 12 years of age. Sixteen children had underlying glomerular disease while eleve...

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ژورنال

عنوان ژورنال: Pediatric Nephrology

سال: 1998

ISSN: 0931-041X,1432-198X

DOI: 10.1007/s004670050390